Heart Health: Long-Term Melatonin Use Linked to Cardiovascular Risk
New research indicates that using melatonin supplements for over a year may increase the risk of heart failure in people with insomnia compared to those who do not use the sleep aid. The study shows that long-term melatonin users were more likely to be diagnosed with heart failure, require hospitalization for this condition, or die from any cause.
This research will be presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans. However, the study is preliminary and has not yet been published in a peer-reviewed scientific journal.
Study Limitations and Safety Concerns
The researchers emphasize that the findings do not prove a cause-and-effect link between melatonin use and heart failure. Still, the results raise concerns about the safety of long-term melatonin supplementation and highlight the need for further research into its cardiovascular effects.
Regulation and Usage Issues
Many melatonin supplements are available over-the-counter without prescriptions, meaning they are not regulated and can be used without medical supervision. Researchers warn,
“Melatonin supplements may not be as harmless as commonly assumed."
Author’s Summary
Long-term melatonin use may pose cardiovascular risks, urging caution and further study to better understand its safety profile.