Concerns About Long-Term Use of a Common Supplement
New research on a widely used sleeping aid has raised concerns among scientists regarding its extended use. An analysis involving over 130,000 adults with insomnia from various countries suggests a link between long-term melatonin prescription and increased heart risks.
Key Findings of the Study
- Adults prescribed melatonin for more than one year showed an 89% higher risk of heart failure over five years compared to those not taking the supplement.
- The long-term melatonin group was twice as likely to die from any cause.
Context and Cautions
These results, which have not yet undergone peer review, do not alter current health guidelines and do not prove that melatonin causes heart problems. Melatonin remains the fourth most popular natural product among US adults, typically regarded as safe for short-term use.
Melatonin is generally safe and well-tolerated for short-term use in those who are not pregnant or breastfeeding, usually for 1 to 2 months.
Limited research exists on the effects of melatonin beyond this period, prompting calls from some experts for further studies as its use continues to rise.
Research Presentation
The findings were presented recently at the American Heart Association's Scientific Sessions.
Summary
This preliminary research highlights the need to carefully investigate melatonin's safety in long-term use, despite its accepted short-term safety profile.